Case Report: Primary HPV-Negative Vaginal Cancer
Primary HPV-negative vaginal cancer is extremely rare, with only 18,000 cases reported globally. This case report highlights the importance of timely biopsy.
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Rare case
Our Most-Read Stories That Connect Science and Human Experience
From medicine and ethics to music, environment, and human resilience, these are the most-read Unknown Focus stories of 2025 and early 2026.
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Case Report: Managing a Rare Parapharyngeal Ganglioneuroma in a Young Girl
A rare tumor was found by chance in a 16-year-old girl after a head injury.
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Rare Case: Fish Bone Mimicking Urachal Cancer
A swallowed fish bone migrated through the body and formed a mass that mimicked urachal cancer.
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Japanese Scientists Report First Human-to-Human Transmission of SFTS Virus
Japanese scientists confirm the first human-to-human transmission of the SFTS virus, highlighting the importance of protection and prevention.
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Rare Case: One Patient, Three Kidneys
A 63-year-old patient with three kidneys, an extremely rare condition, with fewer than a hundred cases reported in the medical literature.
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Portuguese Scientists Report Rare Penile Melanoma
Rare penile melanoma with aggressive behavior, accounting for less than 1% of all cancers.
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Japan Reports First Bloodstream Infection from C. metallidurans
Japanese scientists report the first case of C. metallidurans bloodstream infection in Japan—the sixth case recorded worldwide—in a 77-year-old patient.
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A Rare Case of Primary Malignant Melanoma of the Bladder
Bladder melanoma is an extremely rare tumor, accounting for less than 0.2% of all melanomas; a case of primary bladder melanoma was published in October.
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